Since it skips the GI tract, there are no dietary restrictions at the effective dose of 6 mg every 24 hours, which means you might not need to give up on beer and cheese just yet.Īnother old-school medication category from the 1950s.
DEPRESSION MEDICATION TO TAKE AS NEEDED PATCH
One notable difference from other MAOIs is Emsam’s unique delivery system-it’s the first transdermal patch for depression (all the others are pills). Thought to control posture, movement, and mood, dopamine is also involved with positive reinforcement and dependency. Still, this category of drugs remains an effective option for people whose depression hasn’t responded to SSRIs and SNRIs.Ī new MAOI called selegiline-sold under the brand names Emsam, Eldepryl, and Zelapar-works by selectively blocking monoamine oxidase B (MAO-B) from metabolizing dopamine. MAOIs can also put a major cramp in your diet.įor example, your blood pressure can spike dangerously high if you take MAOIs and eat tyramine-rich foods like aged cheese, cured meats, beer, and soy sauce. These drugs aren’t used as often today because they’re associated with unpleasant side effects (the usual sexual problems and dizziness) but also have potentially dangerous interactions with other antidepressants, seizure medications like carbamaze, and even decongestants like Sudafed (pseudoephedrine, phenylephrine), which can trigger a hypertensive episode. It worked by stopping an enzyme called monoamine oxidase from breaking down neurotransmitters like serotonin, norepinephrine, and dopamine in the brain. These were the first antidepressant category, born way back in the 1950s when doctors found that a derivative of a tuberculosis-fighting drug called Marsilid (iproniazid) helped relieve the symptoms of depression. When patients are feeling desperate, the last thing they want to hear from their doc is that it may take weeks or even months to figure out a solution. This process can be frustrating for doctors and patients. If you don’t respond to a particular medication or a class of drugs, your doctor will try another. If you're already falling asleep at 2 p.m., they won't pick meds associated with fatigue. For example, if you have an eating disorder or are concerned about weight gain, they'll go for a drug that doesn't affect weight. Where do they even start with meds? Psychiatrists know a medication won’t work if a patient stops taking it early because of side effects or feeling like it isn’t “kicking in.” So they often choose your first-line treatment based on side effects that'll be a deal breaker for you. Your doctor may prescribe one (or more) of several types of antidepressants and/or atypical antipsychotic pills to customize an effective treatment.
DEPRESSION MEDICATION TO TAKE AS NEEDED TRIAL
That means trial and error is simply part of the treatment experience. Those genetic tests that claim to take away the guesswork from medication choices? They can tell you which drugs you won’t and will metabolize well, but there’s no telling which of the latter will work better for you. But prepare yourself: There are a slew of pill options, and doctors can't predict who's going to respond best to which ones. And on the right treatment, that will happen. You may be eager to start meds-we get it, you want your symptoms tamped the hell down.
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